Clinical outcome of Low dose intravesical BCG therapy for Non muscle invasive bladder cancer (NMIBC)

Authors

  • Rajan Koju Department of Urology, Dhulikhel Hospital, Kathmandu University Hospital, Dhulikhel, Nepal.
  • Vijay Sharma Department of public health, KUSMS, Banepa, Nepal.
  • Arun Shah Department of Urology, Dhulikhel Hospital, Kathmandu University Hospital, Dhulikhel, Nepal.

DOI:

https://doi.org/10.61122/jkistmc368

Keywords:

Bacillus Calmette-Guerin (BCG), Non Muscle invasive bladder cancer (NMIBC), trans-urethral resection of bladder tumor (TURBT)

Abstract

Introduction: Intravesical Bacillus Calmette-Guerin (BCG) is one of the most effective therapy for Non Muscle invasive bladder cancer (NMIBC), however, due to adverse effects many patients failed to continue treatment. Main objective of this study is to find out efficacy of low dose intravesical BCG in reducing adverse effect without compromising recurrence of tumor.

Methods: This is Cross sectional prospective study which include 39 patients who underwent trans-urethral resection of bladder tumor (TURBT) for bladder mass and histopathology (HPE) report is NMIBC receiving induction or maintenance intravesical BCG from 15th July 2025 to 30th November 2025 at Dhulikhel Hospital, Kathmandu university hospital.  

Results: Mean age is 62.38 ± 10.74 years, 28 Male (71.79%) and 11(28.21%) Female patient. Majority of patients (82.05%) received 60mg intravesical BCG. Adverse effect was noted in 12.82% all are genitourinary symptoms. Recurrence is noted in 12.82% of patients.

Conclusion: Low dose of intravesical BCG for NMIBC is as effective as standard dose with similar recurrence rate and decreased adverse effects.  

 

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Published

2026-01-31

How to Cite

1.
Koju R, Sharma V, Shah A. Clinical outcome of Low dose intravesical BCG therapy for Non muscle invasive bladder cancer (NMIBC). J. KIST Med. Col [Internet]. 2026 Jan. 31 [cited 2026 May 1];8(15):31-4. Available from: https://www.jkistmc.org.np/jkistmc/index.php/JKISTMC/article/view/368

Issue

Vol. 8 No. 15 (2026): Journal of KIST Medical College

Section

Original Article

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Copyright (c) 2026 Rajan Koju, Vijay Sharma, Arun Shah

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